Respuesta :
Answer:
Tumor suppressor genes are cellular proteins that normally function to prevent tumor development, and retinoblastoma typifies the behavior of a classical tumor suppressor gene.
The mechanism that is least likely to inactivate a tumor-suppressor gene is the chemical modification
Explanation:
Anti-oncogene or tumor suppressor gene is involved in the regulation of cell division and replication. These genes are capable of causing cancer when turned off.
The correct answer is:
Option D. Chemical modification.
The Tumor-suppressor gene regulates cell division and can cause cancer when inactivated.
The inactivation can be due to:
- The mutation is the epigenetic and genetic alteration of the genes that can lead to the inactivation of the tumor-suppressor gene.
- Loss of heterozygosity is a type of mutation in which deletion of genetic sequence carrying the tumor suppressor genes is deleted, therefore, leading to inactivation.
- Chemical modification is the addition, deletion, or modification of macromolecules like proteins through a chemical reaction. It is the least cause involved in the inactivation of the tumor suppressor gene.
Thus, the correct option is chemical modification.
To know more about tumor-suppressor genes, refer to the following link:
https://brainly.com/question/16188646
