Malonyl-CoA is an intermediate in fatty acid synthesis. It also regulates fatty acid metabolism. Which of the molecules regulate the enzyme that catalyzes malonyl‑CoA synthesis? carnitine acetyl-CoA oxaloacetate fatty acids or fatty acyl-CoA citrate Which of the enzymes does malonyl‑CoA regulate? carnitine acyltransferase acyl-CoA dehydrogenase fatty acid synthase ATP-citrate lyase acetyl-CoA carboxylase Determine how each of the choices affects fatty acid synthesis and β‑oxidation. inhibits fatty acid synthesis inhibits β‑oxidation Answer Bank

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Answer:

Fatty acid is the the molecule that regulates the enzymes that catalyzes malonyl -CoA  synthesis.  This enzyme is  Acetyl- Co-A carboxylase. It catalytic activity is regulated fatty acid by covalent modification and allosteric control.

Carnitine acytransferase is the enzyme that malonyl-CoA regulates. The latter prevents fatty acids from combining with carnitine, therefore blocking their entry into the mitochondria,inhibiting  fatty acid oxidation and degradation

If the concentration of fatty acid in the cytosol is increased,the production of fatty acid in the cell is inhibited. Likewise beta -oxidation synthesis is inhibited with high concentration of  Melonyl-CoA.

Explanation:

The production of the fatty acids from NADPH and acetyl Co-A with the aid of enzymes is called fatty acid synthesis.

1. The correct answer is:

Option D. fatty acids or fatty acyl-CoA.

  • It is the particle that controls enzymes catalyzing the synthesis of malonyl Co-A.

  • The enzyme that catalyzes the formation is Acetyl- Co-A carboxylase. The allosteric and covalent alterations are influenced by the catalytic actions of the enzyme in fatty acid synthesis.

2. The correct answer is:

Option A. Carnitine acyltransferase.

  • It is the enzyme accountable for managing the malonyl-CoA activity. Malonyl-CoA represses fatty acids to couple with the carnitine.

  • This forbids their approach into the mitochondria that further leading to the restriction of fatty acids repression and degradation.

3. When the concentration of malonyl-CoA is huge then the formation of beta-oxidation gets repressed.

Similarly, due to the high concentration of fatty acids in the cytosol, fatty acid assembly in the cell is hindered.

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