The standard free energy change in physiological conditions (G') for the reaction catalyzed by malate dehydrogenase in the citric acid cycle malate + NAD+ oxaloacetate + NADH + H+ is ~+29 kJmol-1 Calculate the actual G' at 37C if Keq' is 1.02 × 10-5

Respuesta :

Answer: The actual value of [tex]\Delta G[/tex] is -618 J/mol

Explanation:

Relation of ree energy change and equilibrium constant

[tex]\Delta G=\Delta G^0+2.303\times RT\times \log K_{eq}[/tex]

where,

[tex]\Delta G[/tex] = Free energy change

[tex]\Delta G^o[/tex] = standard free energy change = +29 kJ/mol =

R = universal gas constant

T = temperature = [tex]37^0C=(37+273)K=310K[/tex]

[tex]K_{eq}[/tex] = equilibrium constant = [tex]1.02\times 10^{-5}[/tex]

[tex]\Delta G=+29000J/mol+2.303\times 8.314J/Kmol\times 310K\times \log (1.02\times 10^{-5})[/tex]

[tex]\Delta G=29000J/mol-29619J/mol=-618J/mol[/tex]

The actual value of [tex]\Delta G[/tex] is -618 J/mol