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Cohesin protein. Select all that apply. Select all that apply. It comprises filaments in mitotic and meiotic spindles. It prevents sister chromatid separation until anaphase of mitosis or anaphase II or meiosis. It is required for the segregation of chromosomes during anaphase of mitosis or meiosis. It is important for maintaining homologous chromosome pairing and plays a role in recombination. It holds sister chromatids together after chromosome replication.

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marianaegarciaperedo

Answer:

  • It prevents sister chromatid separation until anaphase of mitosis or anaphase II of meiosis
  • It is important for maintaining homologous chromosome pairing and plays a role in recombination.
  • It holds sister chromatids together after chromosome replication.

Explanation:

Cohesin proteins are many protein subunits united and forming a complex that plays an important role in mitosis and meiosis. These complexes have many functions and are involved in DNI repairing or genetic expression, among others. But one of the most known functions is the one of keeping sister chromatids together during cellular division.

  • This function can be accomplished since the S phase of cellular division when chromosomes are replicated. The two new copies must stay together during the G2 phase and the cohesin proteins are the ones in charge of doing so until it is needed.  
  • During the G2 phase of mitosis, sister chromatids are held together until they reach the Anaphase, during which other enzymes are activated to break the bonds and separate the chromatids.  
  • During the G2 phase of meiosis, sister chromatids and homologous chromosomes are held together by the cohesin proteins. Homologous chromosomes must be together until crossing over is completed, and cohesin proteins play an important role in making in possible. After the firsts stages of meiosis, sister Chromatids get completely separated in Anaphase II. During this phase it occurs the same as in mitosis, bonds break and chromatids get separated and go forward each cellular pole.

ayfat23

Statements that are correct as regards Cohesin protein are,:

It prevents sister chromatid separation until anaphase of mitosis or anaphase II of meiosis

It is important for maintaining homologous chromosome pairing and plays a role in recombination.

It holds sister chromatids together after chromosome replication.

  • Cohesin  can be regarded as a protein complex which brings about mediation of sister chromatid cohesion as well as as homologous recombination, and DNA looping.

  • It usually holds sister chromatids together when chromosome replication has been done.

Therefore, Cohesin is essential in maintaining homologous chromosome pairing.

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