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Autocrine:Autocrine signaling means the production and secretion of an extracellular mediator by a cell followed by the binding of that mediator to receptors on the same cell to initiate signal transduction. A well-characterized form of autocrine signaling is the secretion of IL-1 by macrophages.

Juxtacrine:In biology, juxtacrine signalling (or contact-dependent signalling) is a type of cell–cell or cell–extracellular matrix signalling in multicellular organisms that requires close contact. ... A membrane ligand (protein, oligosaccharide, lipid) and a membrane protein of two adjacent cells interact.

Endocrine:The endocrine system is the collection of glands that produce hormones that regulate metabolism, growth and development, tissue function, sexual function, reproduction, sleep, and mood, among other things.

Paracrine:Paracrine signaling is a form of cell signaling or cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behaviour of those cells. ... However, the exact distance that paracrine factors can travel is not certain.

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