Answer:
There are specific receptors present on the surface of the normal cell membrane to recognize the molecules to allow them to pass or not. Most of the bacterial toxin are water-soluble molecules, and bound to the cell surface and interact with them as some time antibody-antigen interaction or cell recognition does not occur that form a pore in the cell membrane and toxins move into the cell.
Once toxins enter the cell they attack intracellular targets through endocytic vesicles. Ultimately these ends in cell death.
The cells are not able to stop the flow of the mentioned harmful substances into the cell as they fail to recognize them as foreign entities. These foreign toxins have intracellular targets with which they bind and lead to death of the cell.
The plasma membrane is formed of lipids. The toxins produced by the bacterial cells are water soluble. Therefore, they identify particular receptors on the membrane and associate with them. Thus, cell at certain occasions fail to identify them as foreign entities.
They combine with the plasma membrane of the cell and induce pore formation, however, there are many toxins that invade the cell and possess intracellular targets via endocytic vesicles. With the help of these vesicles, they deliver their enzymatic domain into the cytosol and results in the death of the cell by obstructing the metabolism of the cell.
Thus, cells fail to identify the bacterial toxins as foreign entities and they invade the cell and results in cell death.
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