Answer: The main similarity between the serine protease and aspartic protease is that these enzymes catalyze the break down or hydrolysis of the peptide bonds.
Explanation:
Serine protease structure has a triad of histidine, serine, and aspartic acid that are joined with the hydrogen bonds. Aspartic protease has a structure which includes the two aspartic acid residues which attack the peptide bond.
Serine protease catalyzes the hydrolysis of the peptide bonds with the the help of two tetrahedral intermediates, whereas the aspartic protease abstracts the proton from water molecule it results in nucleophilic attack on the carbonyl atom of carbon resulting in breakage of peptide bond.
