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A stimulus can be internal, or from within the organism itself. A stimulus can also be external, meaning it occurs outside the organism. Both internal and external stimuli can cause a response, or resulting reaction, in an organism.
External stimuli are changes outside the body, or knowledge that is passed to us through our senses. This could be cold or hot weather, light levels, or danger. Internal stimuli are changes to conditions inside the body, such as dangerous food in the stomach, viruses in the body, or lack of food or water.