How did Jefferson’s policies differ from those of the Federalists?

Answer:
Federalists had a loose interpretation whereas the Jefferson Republicans had a strict interpretation.
Explanation:
Federalits such as Alexander Hamilton had a loose interpretation of the Constitution and believed in a strong federal government, Jeffersionian Republicans disagreed since they favored a limited federal government due to their strict interpretation of the Constitution. For instance Hamilton wanted the creation of a central bank whereas Jefferson opposed it.