Drag the labels to complete each sentence that discusses the development of viral-induced cancer.
1. During the normal functioning of the eukaryotic cell cycle____________ proteins are essential to ensure errors are not perpetuated throughout the cell line.
2. Two important genes that code for these proteins are __________, that initiate cell division at the appropriate time, genes, which control the cycle checkpoints.
3. Viruses can disrupt the expression of these genes; mutation in a proto-oncogene results in the initiation of cell division in the ________of the appropriate signal.
4. Mutation in a tumor-suppressor gene renders the protein __________allowing uncontrolled division of the cell.
5. Cells that have lost the ability to undergo ________as is the case when the____________ tumor-suppressor gene is mutated, will develop into a tumor.
a. apoptosis
b. inactive
c. p53
d. proto-oncogenes
e. presence
f. absence
g. regulatory
h. Myc
i. tumor-suppressor
j. active