Answer:
it may lead to the arrest of the cell division cycle
Explanation:
The presence of DNA double-strand breaks (DBS) during cell division generally leads to the activation of cell cycle 'surveillance' checkpoint mechanisms. The surveillance mechanisms act to ensure the correct functioning of the cell during its division, controlling the order and fidelity of the events during the cell cycle. Some of the most important surveillance mechanisms include spindle assembly checkpoint, proper cell size, replication/integrity of the chromosomes, etc. If surveillance mechanisms detect a problem with the DNA (e.g., a DBS), they will lead to the arrest of the cell division cycle, and the cell will try to either complete DNA replication or repair its damaged DNA. When DNA damage is irreversible, surveillance mechanisms may trigger programmed cell death (apoptosis).
The most likely effect on cell division for a cell containing DNA with double-strand breaks is to arrest the cell division cycle.
Cell division may be defined as the process by which cells multiply involving both nuclear and cytoplasmic division.
In between the phases of the cell cycle, there are checkpoints that ensure the correct functioning of cells during the whole process of cell division. These checkpoints analyze all the procedure of the cell and then sends it to the next phase. If a cell containing a double-strand breaks, it may activate the checkpoint surveillance and arrest the cell till all the functions make normal.
Therefore, the most likely effect on cell division for a cell containing DNA with double-strand breaks is to arrest the cell division cycle.
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