Respuesta :
Answer:
A would probably be the best answer for this question.
Explanation:
Substance abuse is when somebody takes too much of physcioactive drugs which can result in physical or mental instability or harm.
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Answer:
A
Using both words in the sentence, you will know this:
substance: commonly a drug, or liquor
abuse: doing it excessively.
So, what you learn at the end: doing a drug/liquor excessively. The answer choice that makes the most sense here in a negative tone is A.