The frequency of a lethal allele in a population is greatest when it is: Group of answer choices dominant manifested in infancy recessive co-dominant

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Answer:

recessive

Explanation:

A lethal allele is a gene variant associated with a mutation in an essential gene, which has the potential to cause the death of an individual. In general, lethal genes are recessive because these alleles do not cause death in heterozygous individuals, which have one copy of the normal allele and one copy of the allele for the lethal disease/disorder. In recessive lethal diseases, heterozygous individuals are carriers of the recessive lethal allele and can eventually pass the 'defective' allele on to offspring even though they are unaffected; whereas dominant lethal diseases are caused by dominant lethal alleles, which only need to be present in one copy to be fatal. In consequence, the frequency of recessive lethal alleles is generally higher than dominant lethal alleles because they can be masked in carrier individuals. Some examples of human diseases caused by recessive lethal alleles include, among others, Tay-Sachs disease, sickle-cell anemia, and cystic fibrosis.

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The frequency of a lethal allele in a population is greatest when it is: C. recessive.

A lethal allele can be defined as an allele that is responsible for the death of a living organism, especially by preventing its development. Thus, a lethal allele causes a complete mortality in the living organism carrying it, in a hom-ozygous condition.

Basically, a lethal allele is recessive in nature because it is expressed in the phenotype of an organism. Some examples of diseases caused by lethal alleles in humans are:

  • Cystic fibrosis
  • Sickle-cell anemia
  • Achondroplasia

In conclusion, a lethal allele that is recessive has the greatest frequency in a population.

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