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Answer:

The Russians did establish hospitals at Sitka, Kodiak, Unalaska, and Atka between 1817 and 1821. These offered free treatment to the Natives. The Russians also vaccinated some Natives against smallpox. ... The Aleuts and Alutiiq Eskimos were the most affected by the Russians' presence in Alaska

Answer:

The Unungan, or Aleut, people were the first Alaska Natives to be impacted by being forced into slavery to hunt fur-bearing marine animals for the Russians. The diseases carried by the Russians traveled to Alaska Native people well beyond the areas occupied by the Russians.