wendy45cinto wendy45cinto

09-09-2021
Medicine

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The antibiotic bacitracin binds to bactoprenol after it inserts a
peptidoglycan monomer into the growing bacterial cell wall.

Explain how this can lead to the death of that bacterium

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PiaDeveau PiaDeveau

16-09-2021

Bactoprenol is indeed a peptidoglycan transporters that cycles monomers and places them somewhere at cell wall's growth point.

As bacitracin binds to this bactoprenol, the orientation of the peptidoglycan to the cell membrane fluidizes, allowing potassium ions to move from the protoplasts.

As a result of interfering with cell wall production and changing membrane potential, the bacterial cell is lysed.

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