Read the etymology entry.
antagonize
antagonize (v.) 1630s, "to compete with" (obsolete); 1742, "act in opposition to, struggle against continuously,"
from Greek antagonizesthai "to struggle against, oppose, be a rival," from anti "against" (see anti-) + agonizesthai
"to contend for a prize," from agon "a struggle, a contest" (see agony). Meaning "make antagonistic" is by 1882.
What original language did the word antagonize come from?
O Greek
O Latin
O Middle French
O Middle English