What Serial say at an existential or spiritual level can be summarized as don't judge before you understand, and the moral associated with the purpose of life or religious matters is Love and generosity.
The statement by Serial as regards the existential or spiritual level is about not judging anyone so quickly, that one needs to hear both sides of a story before making conclusion.
Therefore, the moral that can be associated with the purpose of life or religious matters is Love and generosity because if you love you won't judge so quick.
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