Single reads are where one end or the whole of a fragment of DNA is sequenced. These sequences can then be joined together by finding overlapping regions in the sequence to create the full DNA sequence.
Paired-end reads are where both ends of a fragment of DNA are sequenced.
What is the role of computer in DNA sequencing?
Computers are faster
DNA sequence codes for the amino acids that form proteins, and the code had been worked out earlier.
At first, DNA sequence was read from a gel and then summarised to amino acids.
Thus, Single reads are where one end or the whole of a fragment of DNA is sequenced.
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