An infant is receiving a medication that has a narrow therapeutic range. The nurse reviews the medication information and learns that the drug is excreted by the kidneys. When giving the medication, the nurse will assess the infant for:

Respuesta :

The nurse will assess the infant for signs of drug toxicity.

Some drugs have a narrow therapeutic index, which means that there is only a small difference between the minimum effective concentrations and the minimum toxic concentrations in the blood. With such drugs, small increases in dose or in blood/serum concentrations could lead to toxic effects.

Nephrotoxicity can show signs of other types of decreased kidney function, such as decreased urination, swelling from fluid retention and high blood pressure. In some patients, nephrotoxicity can affect other body systems such as the liver or the skin and show signs in those areas as well.

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