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MissPhiladelphia
I believe that the answer to the question provided above is that the westward expansion created a clash between sectional interests in Missouri because of the geographical location of Missouri it was being clashed.
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Tundexi

The expansion lead to economic promise and fueled the manifest destiny but it also lead to sectional tension over slavery.

The westward expansion refers to an expansion of the United States from the late 18th to the mid 19th centuries

Hence, the reason for westward expansion creation of  clash between sectional interests in Missouri is because the expansion lead to economic promise and fueled the manifest destiny but it also lead to sectional tension over slavery.

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