Mutations are changes in the DNA sequence that can cause alteration in signaling pathways, transcription, translation, and epigenetics is a reason that a cell might not be able to create and deliver all the protein it needs.
Mutation can change the instructions of a gene to not make protein at all. It can also cause a protein to malfunction.
It can change the transcription of a nucleotide sequence from DNA to mRNA.
A lack of amino acids can also be a major reason that a cell might not be able to create and deliver the protein.
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