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Grading of newborn MRI brain damage and 2-year neurodevelopmental outcome did not significantly co-relate.

What is Hypoxic-Ischemic Encephalopathy?

Hypoxic-Ischemic Encephalopathy (or HIE) is a broad term for brain dysfunction caused by a decrease in blood flow and oxygen to the brain. HIE is sometimes referred to as birth asphyxia, but this term only applies to infants with brain injury who meet very strict criteria.

Why doesn't it co-relate?

A tertiary university hospital conducted a retrospective cross-sectional study. This study included patients diagnosed with neonatal HIE between 2007 and 2016 who completed 72 hours of cooling therapy and had an MRI brain within two weeks of birth. Trivedi et al. developed a new scoring system that focuses on subcortical deep gray matter and posterior limb internal capsule injury during MRI assessment using TW, T2W, and diffusion-weighted imaging (DWI) sequences. The brain injury was graded as none, mild, moderate, or severe based on the cumulative MRI brain score. Using Fisher's Exact Test, the MRI brain scoring was then correlated with the patient's 2-year neurodevelopmental outcome.

To learn more about MRI brain damage and neurodevelopment, refer: https://brainly.com/question/28537246

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