Option C) In case of overdose of intravenous heparin where patient is showing signs of bleeding, Protamine sulfate is the antidote.
A particular heparin antagonist, proton sulfate, binds to heparin to reverse its anticoagulant effects entirely. Any kind of Warfarin (Coumadin) overdose can be treated with vitamin K.
Protamine has been selected as the solely approved antidote to heparins, notwithstanding its low therapeutic index.
The toxicology of any protamine depends on a complex interaction between the cationic peptide with a high molecular weight and the surfaces of blood cells.
If a person who is taking warfarin or heparin bleeds, needs surgery, they are typically treated with specific antidotes like protamine or vitamin K, respectively at first.
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Complete Question
A patient has received an overdose of intravenous heparin and is showing signs of excessive bleeding. Which substance is the antidote for heparin overdose?
a. vitamin E
b. vitamin K
c. protamine sulfate
d. potassium chloride