There are already too many chloride ions outside of the cell.
Depolarization is characterized in science as the abolition of polarity. Depolarization, however, has a slightly different meaning in physiological systems like cells, where it describes becoming more positively charged than the surrounding air or water. The cells of the nervous system called neurons are made to transmit and receive information.
Neurotransmitters, a class of chemical messengers, and alterations in the environment like pressure, sound, or light can excite neurons. Different ion channels activate in response to the stimulation of a neuron. Positively charged ions, such as sodium or potassium, can enter the neuron if positively charged ion channels are opened, reducing the cell's negative charge and causing it to depolarize.
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