Respuesta :
When pyruvate is used to make one molecule of glucose
- 4 ATP, 2 GTP are used.
- 2 ATP and 2 NADH are generated.
- 4ATP, 2 GTP, and 2 NADH are used.
In gluconeogenesis, glucose is created. It is essentially glycolysis carried out reverse; the standard free energy is favorable thanks to three new processes involving four new enzymes. ATP is used by the gluconeogenesis pathway, which gets its energy mostly from oxidizing fatty acids.
The molecule can be transferred from the mitochondria thanks to the conversion to malate. After entering the cytoplasm, mitochondria convert it back to oxaloacetate.
Malate + NAD+ Oxaloacetate + NADH in the cytoplasm
PEP GDP Oxaloacetate + GTP
It then passes through the same intermediates as glycolysis from this point on. The endoplasmic reticulum hosts the final reaction.
G6P glucose is present in the endoplasmic reticulum (catalyst: glucose-6-phosphatase). A glucose transporter shuttles the glucose out into the extracellular space.
For every molecule of glucose synthesized from two molecules of pyruvate, 4 ATP, 2 GTP, and 2 NADH are used.
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