Respuesta :
Lyophilization method of microbial control does not rely on denaturing proteins and/or disrupting the integrity of the cell membrane.
Lyophilization, also known as freeze drying, is a process in which water is removed from a frozen product and placed under a vacuum, allowing the ice to transition from solid to vapor without passing through a liquid phase. Lyophilization is a water removal process that is commonly used to preserve perishable materials, extend shelf life, or make the material more transportable. Lyophilization involves freezing the material, then lowering the pressure and increasing the heat to allow the frozen water in the material to sublimate.
Liquid nitrogen can be used successfully and economically instead of mechanical refrigeration for lyophilization/pre-freezing, increasing viability and yield. It also improves performance and reliability while requiring less capital investment than mechanically based systems.
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