If a cell is no longer able to differentiate into any type of tissue, it has become a differentiated cell.
Cellular differentiation can cause a stem cell to change into a new kind. The cell will typically change into a new type that is more specialized. A multicellular organism undergoes several differentiation cycles as it transforms from a basic zygote to a complex system of tissues and cell types. When adult stem cells divide to become fully differentiated daughter cells during tissue repair and regular cell turnover, they continue to develop. Differentiation is the result of immune responses to an antigen. During differentiation, a cell's dimensions, shape, membrane potential, metabolic activity, and signal receptivity all change significantly.
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