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Gel electrophoresis can be used to differentiate the sizes of duplex nucleic acid molecules. A duplex molecule can be created by joining complementary separate nucleic acid sequences.

What is duplex RNA or DNA?

The duplex structure supports the Watson-Crick base pairing model for GNA containing antiparallel strands. The right-handed helical ribbon that is wrapped around the helix axis to create a big hollow core is how one can define the duplex secondary structure, which is different from the canonical A- & B-form nucleic acids.

How are RNA duplexes created?

One of the most biologic systems is the duplex synthesis of nucleic acids. During replication, RNA primers create a duplex with parental strand of DNA. (1) A brief stretch of duplex must be formed during translation in order to recognize codons against anticodons.

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