What is the correct sequence of events for activation of a b cell by a t-dependent antigen?.

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15-11-2022
Biology

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What is the correct sequence of events for activation of a b cell by a t-dependent antigen?.

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Qwclear Qwclear · Answer 1 · 2022-11-20T08:32:56+01:00

The correct sequence of events for activation of B-cells by T-dependent antigen is recognition of antigen, fragmentation, binding and secretion.

The process can be understood as firstly immunoglobulin receptors on the B cell recognize and bind with the antigen, secondly an antigen fragment in complex with MHC class 2 is displayed on the B cell's surface, thirdly the MHC-antigen complex binds a receptor on a TH cell and finally the TH cell secretes cytokines that activate the B cell. B-cells are the antibody producing cells that produce antigen specific immunoglobin molecule to fight against the pathogens such as bacteria or fungi. These B-cells are found in bone marrow of an individual. Lesser number of B-cells in the body makes it prone to infections as the immune system gets weak. T cells are the types of white blood cells primarily involved in directly killing of infected host cells, activating other immune cells, producing cytokines and regulating the immune response.

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