the physician orders a serum trough drug level for a client who is receiving antibiotic therapy. the client is receiving the drug every 6 hours: at midnight, 6 a.m., noon and 6 p.m. the nurse anticipates that the specimen would be obtained:

Antibiotic treatment is based on susceptibility testing of bacteria isolated from urine, blood or infected tissue (see Chapter 15). 113. Only antibiotic therapy is recommended unless there is severe spinal cord compression or there is no response after five days.

The successful prophylactic use of antibiotics depends on three principles. The individual patient must be at high risk of infection, the likely infecting organisms and their susceptibilities must be known, and prophylaxis must be administered only during times of risk.

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