By introducing one or more nucleotides to the gene, an insertion modifies the DNA sequence. Consequently, the protein produced from the gene might not work effectively.
Frameshift Mutation
If nucleotide bases are added or removed from a gene in amounts that are not multiples of three, this is referred to as a frameshift mutation. This is significant because a cell reads the genetic code for proteins in groups of three nucleotides.
Other forms of mutations that might impact cells at the gene level include insertions and deletions.
The replicating strand slips or wrinkles during an insertion mutation, resulting in the incorporation of the additional nucleotide.
One or a few nucleotides are inserted into the DNA sequence as part of a small-scale insertion mutation. A chromosomal region-specific insertion is a large-scale form of insertion. A nonreciprocal translocation takes place in this instance.
A deletion alters the DNA sequence by removing at least one nucleotide from a gene.
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