The average population fitness can be significantly impacted by a population's mutation rate. For instance, if the rate of mutation rises, the average population fitness tends to decline since there are more deleterious mutations.
A mutation is referred to as a genetic disorder if it negatively affects the phenotypic of the child. Alternately, a mutation is referred to as an adaptation if it improves the fitness of the progeny.
In natural systems, such as viruses, bacteria, and human malignancies, genetic changes frequently lead to a rise in the mutation rate. An increase like this encourages the accumulation of frequently neutral or harmful alleles, although it can also also raise the probability that a population will pick up uncommon advantageous alleles.
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