DNA's double helix is supported by hydrogen bonds, which also provide the base pairings A-T and G-C.
Topoisomerases (red) (red) minimize torsional strain brought on by DNA double helix unwinding; DNA helicase (yellow) breaks hydrogen bonds between complementary base-pairs; single-strand binding proteins (SSBs) stabilize the split strands and stop them from coming back together.
The Enzymes called helicases can modify or bind to nucleic acid or nucleic acid protein complexes. Both DNA and RNA have helicases. Because they convert double-stranded DNA into single-stranded DNA, DNA helicases are necessary for DNA replication.
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