Respuesta :
Temperature, pH, PCO2, and 2,3 diphosphoglycerate are some of the variables that affect how oxygen binds to hemoglobin.
The oxygen dissociation curve moves to the right and Hb's affinity for O2 decreases as its temperature rises. The oxygen Hb dissociation curve changes to the right as the partial pressure of carbon dioxide rises, increasing the P50 value. As a result of greater Hb binding to carbon dioxide, Hb has a lower affinity for oxygen.
- High pO2: The more oxygen there is in the air, the more effectively haemoglobin binds to oxygen.
- Low pCO2: Oxyhemoglobin production is reduced by a lot of carbon dioxide. Compared to oxygen, carbon dioxide has a stronger affinity for hemoglobin.
- Less H+: Hemoglobin is more likely to dissociate when the pH is lower or the hydrogen ion concentration is higher.
- Lower temperature: Hemoglobin and oxygen are more likely to bind at a normal temperature. The oxygen separation from haemoglobin is caused by the high temperature.
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