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The transport of glucose from the blood to the cell is accomplished by Facilitated diffusion mechanism .

The process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological membrane by certain transmembrane integral proteins is known as facilitated diffusion (also known as facilitated transport or passive-mediated transport). Due to the fact that it is passive, facilitated transport does not directly require chemical energy from ATP hydrolysis during the transport step itself. Instead, molecules and ions travel along their concentration gradient, indicating the fact that the process is diffusive.

Simple diffusion and facilitated diffusion are different in a number of ways.

The carrier protein or membrane-embedded channel must bind to the cargo molecularly for the transport to take place.

In contrast to free diffusion, which is linear in the concentration difference, the rate of assisted diffusion is saturable with regard to the concentration difference between the two phases.

Due to the presence of an active binding event, the temperature dependency of assisted transport differs significantly from that of free diffusion, where the influence on temperature is minimal.

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