The steps in order are:
1) recognize damaged site
2) separate strands using helicase
3) hydrolyze incorrect nucleotide using endonuclease
4) fill in gap with DNA polymerase
5) close DNA ends with DNA ligase
A significant DNA repair system known as nucleotide excision repair (NER) may remove a variety of helix-distorting DNA lesions that are mostly caused by environmental mutagens like ultraviolet light (UV) irradiation and large chemical compounds.
A method of repairing DNA is called nucleotide excision repair. Chemicals (e.g., intercalating agents), radiation, and other mutagens continually induce DNA damage.
The steps in order are:
1) recognize damaged site
2) separate strands using helicase
3) hydrolyze incorrect nucleotide using endonuclease
4) fill in gap with DNA polymerase
5) close DNA ends with DNA ligase
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