Mutations, which are modifications to a gene's DNA sequence, can sometimes alter the amino acid sequence of the protein for which the gene codes.
Although a mutation at specific places, such as conserved residues, might affect both the protein's structure and function, it is not always the case that a mutation in the amino acid sequence would modify a protein's structure.
A protein's function may vary or disappear totally if just one amino acid in its sequence is altered. The building blocks of proteins are amino acids.
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