The pathophysiological process responsible for the hemolytic-uremic syndrome is d. verotoxin from e. coli is absorbed from the intestines and damages erythrocytes and endothelial cells.
The hemolytic uremic syndrome is an immune system disorder that causes kidney failure, thrombocytopenia (low levels of platelets), and anemia (low levels of red blood cells). Disorders of the immune system most often occur after an infection in the digestive tract.
The hemolytic uremic syndrome is the most common cause of acute kidney failure in children.
The toxins contained in the germs that cause digestive infections trigger an overreaction of the immune system. This results in excessive destruction of red blood cells and platelets. In addition, excessive immune reactions also cause injury to the kidneys.
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