On the cytoplasmic side of the plasma membrane, Gene Ontology Term (GO:0009898) Those proteins that are embedded, anchored, or adhered to the surface of the leaflet of the plasma membrane that confronts the cytoplasm are defined.
The term "transmembrane proteins" refers to proteins that span the whole membrane. An integral membrane protein typically has hydrophobic and hydrophilic regions, with the former being located inside the membrane and the latter being found outside of it. These compartments, in the case of the plasma membrane, are the cell's inside and exterior. The particular tasks of the plasma membrane, such as selective chemical transport and cell-cell identification, are carried out by proteins embedded inside the phospholipid bilayer.
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