The toughest substance created through biological processes is enamel. It makes up the anatomical crown of a tooth and is derived from the epithelium.
The pulp and dentine of the tooth are made by the ectomesenchyme, whereas the enamel of the tooth is made by the oral epithelium. Deep within the oral epithelium is the ectomesenchyme. Ectoderm and mesoderm from the embryonic germ layer evolve into teeth. The oral cavity's ectoderm forms the enamel portion, while the related mesenchymal cells form all other tissues. The makeup of enamel. All mineralized tissues in vertebrates, including the enamel, contain about 95 weight percent (carbonated) apatite, a calcium phosphate mineral (3). Apatite crystals primarily grow along their c-axis and have elongated forms as a result.
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