The probability of having a son with hemophilia is 25% (or one in four). a 25% possibility of having a son that clots normally. a 25% possibility of having a carrier daughter. having a daughter with hemophilia has a 25% risk.
Should the father have hemophilia: As a result of receiving their mother's healthy X chromosome, none of his sons will be affected by hemophilia, but his daughters have a 50/50 chance of carrying the condition.
Overall, each pregnancy has a 1 in 4 (25%) chance of producing a male with hemophilia and a 1 in 4 (25%) chance of producing a daughter who is heterozygous.
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