It is true that the growth hormone axis contains at least one example of a negative feedback loop.
Two different kinds of negative feedback loops are involved in controlling the hypothalamus-pituitary axis. Long-loop feedback and short-loop feedback are the two types.
The growth hormone-releasing hormone (GHRH) synthesis and secretion from the hypothalamus are blocked by pituitary hormones in short-loop feedback. This will result in the inhibition of GH secretion.
In long-loop feedback, the release of insulin-like growth factor 1 (IGF-1) from the endocrine part of the liver blocks the GHRH secretion and synthesis by the anterior pituitary and the hypothalamus. This also thus results in the inhibition of GH secretion.
Therefore, the statement is true.
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