The symptoms of diphtheria are due to an exotoxin that blocks proteins synthesis in host cells is true.
So the correct answer is option B.
The pathogenic bacteria Corynebacterium diphtheriae, which secretes the exotoxin diphtheria toxin, is what causes diphtheria. The corynephage prophage, which infects cells and prevents protein synthesis, is what causes disease in humans. It carries the toxin gene.
A-B toxin or diphtheria toxin is a single polypeptide chain of 535 amino acids that is made up of two subunits connected by disulfide bridges. The A subunit of the protein, which is more stable, enters the host cell after the B subunit, which is less stable, adheres to the cell surface.
To 2.5 ngstrom resolution, the crystal structure of the homodimer of diphtheria toxin has been established. Three domains make up the Y-shaped molecule that the structure has shown.
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