The structure or component of the small intestine that is important to antimicrobials are Paneth cells. So option c. is correct.
Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef Paneth as columnar epithelial granules in their cytoplasm. Decades later there is continued interest in Paneth cells as they play an integral role in maintaining intestinal homeostasis and modulating the physiology of the small intestine and its associated microbial flora.
Paneth cells are highly specialized secretory epithelial cells located in the small intestinal crypts of Lieberkuhn. The dense granules produced by Paneth cells contain an abundance of antimicrobials.
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