Given that about 25% of the mammalian genome is associated with genes, including introns and regulatory sequence, 40,000 base pairs would be the approximate average length of DNA per gene, if the genome contained 20,000 genes.
Mammalian Genome is a community-reviewed publication that publishes studies and review articles in mouse, human, and related organism genetics and genomics.
Most mammalian cells possess two or four copies of the genome, and sometimes even cells with the same amount of genomes can vary significantly in size; thus, DNA concentration varies dramatically from cell to cell.
Mammalian cell bundle their DNA into chromatin and organize it as chromosomes in the nucleus. Chromosomes are organized radially in interphase cells, putting the most gene-dense chromosomes toward the central core of the nucleus.
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