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ou work in a lab and you have discovered a brilliant way to specifically control chromatin remodeling on a gene by gene basis. You work in a lab and you have discovered a brilliant method for targeted control of chromatin remodeling on a gene-by-gene basis. You are specifically interested in modifying the transcription of oncogenes, which are genes whose overexpression can lead to cancer. Select modifications you would make in cancer cells that are over expressing oncogenes. Check all that apply. Check All That Apply Increase acetylation of histones Decrease acetylation of histones Decrease phosphorylation of histones Increase phosphorylation of histones Increase methylation of histones Decrease methylation of histones

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Being specifically interested in modifying the transcription of oncogenes, decrease acetylation of histones is the modifications you would make in cancer cells that are over expressing oncogenes.

Each histone molecule includes a long tail wealthy in essential amino acid residues (K), that are acylation modification sites. Sequence activation and repression are regulated by acylation of core histone, and simple protein acylation is mediate by coactivators and corepressors

Cells with mutations in these genes tend to develop further mutations in different genes and changes in their chromosomes, like duplications and deletions of body elements. Together, these mutations could cause the cells to become cancerous. Cancer cells  divide regularly, forming solid tumors or flooding the blood with abnormal cells. organic {process|biological process} may be a traditional process utilized by the body for growth and repair.

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