The bending of a tip link protein leads to depolarization of the hair cell by allowing potassium ions to diffuse across the membrane into the cell.
The transmission of auditory impulses is the organ of Corti's main purpose. The auditory canal allows sound waves to enter the ear, where they cause the tympanic membrane to vibrate. Tympanic membrane movement results in vibrations in the middle ear's three ossicles, which then transmit energy to the cochlea through the oval window. Waves go through the perilymph fluid in the scala tympani and then the scala vestibuli of the cochlea when the oval window moves. The tectorial membrane replaces the basilar membrane, which is situated between the scala media and scala tympani, as fluid passes between these structures.The cochlea's scala media houses an inner ear organ called the organ of Corti (Figure 1A). It is located on the basilar membrane, a hard membrane that divides the scala media from the scala tympani (Figure 1A). Endolymph with a high (150 mM) K+ content is found in the cochlea cavity known as the scala media. The electrical impulses of the auditory hair cells are regulated in part by the endolymph.
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