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hemophilia a is an x-linked recessive disorder characterized by lack of a functional factor viii, a protein involved in blood clotting. in one population, the frequency of the normal allele, x 1, is 0.98 and the frequency of the mutant allele that causes hemophilia a, x 2, is 0.02.

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In this population, hemophilia A affects 2% of the males.

Why is hemophilia A a condition that is X-linked recessive?

Due to the fact that males only have one X chromosome, hemophilia is a hereditary condition that is X-linked and recessive in nature. Females are typically carriers since they have an extra X chromosome, however heterozygous carriers frequently exhibit hemophilia symptoms.

Is factor 8 a problem with blood clotting?

The Hemophilia is an additional genetic clotting condition that involves factor VIII. Von Willebrand disease, however, affects both sexes equally and is typically more mild than hemophilia, which primarily affects men.

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