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p16 is a tumour suppressor protein that functions as a cyclin-dependent kinase inhibitor and is required for cell cycle regulation. Because p16 inhibits cyclin-dependent kinases that phosphorylate Rb, it can slow down the cell cycle.
Tumor suppressor genes encode which type?
Tumor suppressor genes, also known as anti-oncogenes, encode proteins that transduce negative cell growth regulatory signals such cell cycle arrest and death.
The TP53 gene codes for the production of a protein known as tumour protein p53 (or p53). This protein functions as a tumour suppressor, which means it controls cell division by preventing cells from growing and dividing (proliferating) too quickly or uncontrollably.
Cyclins and cyclin-dependent kinases are two types of proteins that promote the cell cycle.
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