Under normal conditions, the epithelial cells of the collecting duct are impermeable to water but can absorb about 5% of the total amount of sodium found in the filtrate. However, in the presence of aldosterone and ADH, the collecting duct is made permeable to water.
What causes increase in the permeability of the cells of the collecting tubule to water?
Water excretion by the kidney is regulated by the peptide hormone vasopressin. Vasopressin increases the water permeability of the renal collecting duct cells, allowing more water to be reabsorbed from collecting duct urine to blood.
Which nephron segment is impermeable to water?
In contrast to being impervious to water, the ascending limb is permeable to salts (sodium), allowing sodium to seep out and raising the medulla's salt concentration.
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